Search for European Projects

16 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Highly Multiplexed Affinity Proteomics for Point of Care Diagnostics (MultiPOC)

Start date: Apr 1, 2014, End date: Mar 31, 2019,

The main objective is the development of highly multiplexed affinity proteomics tools for point of care diagnostics. Enabled by the world's largest resource of antibodies to human protein targets generated within the framework of the Human Protein Atlas program, the aim of this application is to develop new concepts in translational medical research to allow dramatic improvement in performance and ...
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 2

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DIabetes REsearCh on patient sTratification (DIRECT)

Start date: Feb 1, 2012, End date: Jan 31, 2019,

The overarching aims of the DIRECT consortium, consisting of 20 leading academic groups in diabetes and 5 EFPIA companies, are to identify biomarkers that address current bottlenecks in diabetes drug development and to develop a stratified medicines approach to treatment of type 2 diabetes with either existing or novel therapies.There is heterogeneity in who develops diabetes, the rate at which th ...
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 27

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PRIMES: Protein interaction machines in oncogenic EGF receptor signalling (PRIMES)

Start date: Dec 1, 2011, End date: Nov 30, 2016,

"PRIMES focuses on the role of protein interactions to assemble dynamic molecular machines that receive and process information to coordinate cellular responses. PRIMES investigates the following: (i) How do protein interactions contribute to the generation of biological specificity in signalling? (ii) How do pathogenetic perturbations affect protein interaction networks? (iii) How can we exploit ...
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 14

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The development and evaluation of Multipurpose crops as new biorefining feedstocks for the production of industrial BioProducts and biomass (MultiBioPro)

Start date: Oct 1, 2012, End date: Sep 30, 2016,

The overall strategic objective of MultiBioPro is to exploit natural resources from genetic varieties of two industry-utilized plant species, poplar and the tobacco tree Nicotiana glauca, for direct applicability to novel industrial end products. The consortium will explore already existing poplar and N. glauca genotypes in parallel with innovative state-of-the-art translational research from the ...
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 12

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"High Efficient, Single-Use-Bioreactor simulating mammalian tissue conditions for expression and proliferation" (HESUB)

Start date: May 1, 2013, End date: Apr 30, 2016,

A unique combination of earlier EU funded projects allow four research SME´s to create a combined most visionary and innovative product for improved health. There is a strategic decision from pharmaceutical companies and hospitals for:1. continues expressing of biologicals to fulfill the expectation to “personalized medicine” and 2. proliferation of cells to support therapeutic applications and 3. ...
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 5

 FINISHED 

Magnetic Isolation and moleculaR Analysis of single CircuLating and disseminated tumor cElls on chip (MIRACLE)

Start date: Sep 1, 2010, End date: May 31, 2015,

... in a miniaturized system. This envisaged, fully-automated MIRACLE test would yield decisive results within half a day for less than 50 EUR, as compared with contemporary diagnostics tests that may take days.With the essential individual modules recently demonstrated on automated chips in a joint project by some of the partners involved (MASCOT FP6 027652), the MIRACLE's consortium is uniquely pos ...
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 15

 FINISHED 

European large-scale functional genomics in the rat for translational research (EURATRANS)

Start date: Apr 1, 2010, End date: Mar 31, 2015,

Genetic studies in model organisms and humans, including human genome-wide association studies, have pinpointed genomic regions that contribute susceptibility to common disease. However, to date, these data have provided limited insights into the genes, molecular pathways and mechanisms underlying disease pathophysiology.The EU FP6 Euratools consortium has been a remarkable success that establishe ...
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 19

 FINISHED 

Protein Binders for Characterisation of Human Proteome Function: Generation, Validation, Application (AFFINOMICS)

Start date: Apr 1, 2010, End date: Mar 31, 2015,

The Affinomics programme aims to leverage existing efforts in Europe to generate large-scale resources of validated protein-binding molecules (‘binders’) as affinity reagents for characterisation of the human proteome and to apply them in comprehensive structural and functional analyses of protein expression, interactions and complexes. Proteome targets will be focused on five categories of inter- ...
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 20

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Cancer Genomics of the Kidney (CAGEKID)

Start date: Mar 1, 2010, End date: Aug 31, 2014,

The International Cancer Genome Consortium (ICGC) has the goal of obtaining a comprehensive description of genomic, transcriptomic and epigenomic changes in 50 different tumour types and/or subtypes, with the aim of elucidating the genomic changes present in the many forms of cancers that contribute to the burden of disease throughout the world. We present a proposal for a European contribution to ...
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 15

 FINISHED 

Massive Digital sequencing by binary DNA (Digital Sequencing)

Start date: Dec 1, 2009, End date: May 31, 2014,

DNA sequencing costs have fallen more than 50-fold over the past decade, driven part by tools, technology and process improvements made during the Human Genome Project. However, it still costs around $10 million to sequence 3 billion base pairs - the amount of DNA found in the genomes of humans and other mammals. 1st generation sequencing platforms, which are based upon capillary electrophoresis ...
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 5

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The development of very high performance bioderived composite materials of cellulose nanofibres and polysaccharides (NanoCelluComp)

Start date: Mar 1, 2011, End date: Mar 31, 2014,

The overall aim of the NanoCelluComp project is to develop a technology to utilise the high mechanical performance of cellulose nanofibres, obtained from food processing waste streams, combined with bioderived matrix materials, for the manufacture of high performance composite materials that will replace glass and carbon fibre reinforced plastics in many applications including transportation, wind ...
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 12

 FINISHED 

PROteomics SPECification in Time and Space (PROSPECTS)

Start date: Apr 1, 2008, End date: Mar 31, 2013,

...mogeneous and static entities with little or no quantitative annotation. PROSPECTS (PROteomics SPECification in Time and Space) is a proposal by world leaders in this young discipline to make a major advance, both by developing much more powerful instrumentation and by applying novel proteomics methods that will allow us to annotate quantitatively the human proteome with respect to protein localiz ...
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 11

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European Network for Genetic and Genomic Epidemiology (ENGAGE)

Start date: Jan 1, 2008, End date: Dec 31, 2012,

"ENGAGE (European Network for Genetic and Genomic Epidemiology) has, as its central objective, the translation of the wealth of data emerging from large-scale research efforts in molecular epidemiology into information of direct relevance to future advances in clinical medicine. ENGAGE will do this through the integration of very large-scale genetic and phenotypic data already available from a sub ...
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 26

 FINISHED 

Identifying and validating pre-clinical biomarkers for diagnostics and therapeutics of Neuromuscular Disorders (BIO-NMD)

Start date: Dec 1, 2009, End date: Nov 30, 2012,

... characterisation and therapy in NMDs.OMIC sciences (genomic, transcriptomics, proteomics) offer opportunities to identify biomarkers for finely defining and tuning the NMDs bases. This approach can make available non-invasive biomarkers, to be used for monitoring disease progression, prognosis and drugs response, therefore optimising the choice of appropriate and often personalised therapies. Val ...
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 15

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Improving Plant Cell Walls for Use as a Renewable Industrial Feedstock (RENEWALL)

Start date: Aug 1, 2008, End date: Jul 31, 2012,

...he recalcitrance of cell walls to enzymatic hydrolysis. RENEWALL aims to find ways to overcome this technical bottleneck by identifying and modifying the structural features of plant cell walls that make them difficult to process. Our partnership brings together outstanding biologists, chemists, and enzymologists, as well as industrialists from the plant breeding and biotechnology sectors, from Eu ...
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 17

 FINISHED 

IT Future of Medicine (ITFoM)

Start date: May 1, 2011, End date: Apr 30, 2012,

... for IT, in hardware, storage and communication. We propose a data-driven, individualised medicine of the future, based on molecular/physiological/anatomical data from individual patients. We shall make general models of human pathways, tissues, diseases and ultimately of the human as a whole. Individualised versions of the models, produced for each patient, will then be used to identify persona ...
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