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The scope of this ITN is to promote research and training in the field of chromatin diseases. Chromatin diseases (CD) are genetic pathologies resulting from mutations in structural components of chromatin or in enzymes that biochemically modify chromatin, altering chromatin status and thereby causing drastic effects on gene expression. CD frequency ranges from very rare to quite common pathologies ...

"Implementation of REACH requires demonstration of the safe manufacture and use of chemicals. REACH aims to achieve a proper balance between societal, economic and environmental objectives, and attempts to efficiently use the scarce and scattered information available on the majority of substances. Thereupon REACH aims to reduce animal testing by optimized use of in silico and in vitro information ...