6 European Projects Found
Searched on 125080 European Projects
FINISHED
Translational Research Network in Prostate Cancer (TransPot)
Start date: Jan 1, 2017, End date: Dec 31, 2020,
The Translational Research Network for Prostate Cancer (TransPot) program adopts an innovative, multidisciplinary approach, providing highly sought-after, effective solutions for incurable prostate cancer (PC).The TransPot scientific objective is to obtain an unmatched depth of molecular, mechanistic and informatics systems-level disease understanding in order to improve the prognosis and treatmen ...
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11
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Protein biomarker for the prediction of response to endocrine treatment in breast cancer patients (EndoPredict)
Start date: Feb 1, 2013, End date: Jan 31, 2017,
Classical pathologic parameters have been used to inform adjuvant clinical treatment choices for early breast cancer patients. There remain a significant number of patients however, who despite a reportedly favourable prognostic profile, experience metastatic disease. Elucidation of the mechanisms of tumour adaptability and the identification of predictive markers of early recurrence is the basis ...
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2
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Development of an oral Helicobacter Pylori vaccine (HELICOVAXOR)
Start date: Oct 1, 2012, End date: Dec 31, 2014,
"Helicobacter pylori infection is highly prevalent worldwide and is an important cause of gastritis, peptic ulcer disease, and significantly gastric cancer. Because eradication requires treatment with multidrug regimens, there exists a very strong need for a vaccine to prevent initial infection.Immunization with H pylori protein subunits in humans has shown adjuvant-related adverse effects and onl ...
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11
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Development of OPN-305 as an orphan drug for the treatment of Delayed Graft Function post solid organ transplantation (MABSOT)
Start date: Dec 1, 2010, End date: Sep 30, 2014,
Delayed graft function (DGF) is defined as the need for dialysis within seven days of renal transplantation (DGF promotes allograft rejection, requires prolonged dialysis and hospitalisation, and increases the likelihood of graft failure and ultimately the duration of renal graft survival-expectancy. The incidence of DGF occurs in 21-44% of cases following cadaveric renal graft. Several rare dise ...
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10
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Identification of Clinically Useful Biomarkers for IGF-I Receptor Signalling n Cancer (BIOMARKERIGF)
Start date: Sep 1, 2010, End date: Aug 31, 2014,
...g biomarkers for the IGF-IR signalling pathway in cancer. This programme involves a collaboration between researchers at University College Cork who are experts in IGF-I signalling and researchers at Almac Diagnostics who are experts in pharmacogenomic approaches to biomarker discovery in cancer. The research plan will take two complementary approaches: 1) explore the potential of a list of candid ...
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2
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Understanding inflammation-associated tumorigenesis for the rational design of novel anti-cancer therapeutic strategies (INFLA-CARE)
Start date: Jan 1, 2009, End date: Jun 30, 2013,
Epidemiological and experimental evidence supports a link between chronic inflammation and cancer and indicates a role for inflammatory cells in the initiation, progression and metastasis of malignancy. The objective of the collaborative integrated project INFLA-CARE is to structure a European collective of scientific and technological excellence in the field of ‘Inflammation & Cancer’ which will ...
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