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Drug Discovery in Interacting Proteins (DDIPI)

Start date: Aug 1, 2010, End date: Jul 31, 2014,

...ponses to the latter thereby contributing to type 2 diabetes. A second project will identify the protein machinery involved in the failure of otherwise active natural mutants of the MC4 receptor to traffic to the cell surface. This failure produces 6-7% of cases of gross genetic obesity. The third project will identify native protein ligands for a new family of G-protein coupled receptors (LNB-GPC ...
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